Curriculum (en)

Current position: 


Director of the Bioethics Unit
President of the Ethics Committee
Istituto Superiore di Sanità (ISS, Italian National Institute of Health) 

Vice President of the of the “National centre for the coordination of regional ethics committees for clinical trials of medicines and medical devices for human use”*

Delegate of the ISS on the National Bioethics Committee

Member of the Pontifical Academy for Life

* on having declined the post of President




1. Biographical notes

- Born in Turin, Italy, 1965
- Degree in Biological Sciences, 1988 (110/110 with honour and mention. Prize Sgaravatti)
- Qualification to the Biologist Association, 1990
- Post-university specializations: Bioethics; Communications Sciences
- Cours Universitaires de langue, lettres et civilisation françaises (Université de Paris Sorbonne), 1984 (with honour)
- Prize Superior School of Journalism in Venice Mestre - Centre Kolbe
- Prize Atheste - Education Superintendency of Padua

- Since 2005: Senior researcher, ISS
- 1993-2005: Research assistant, ISS
- 1988-1993: Scholarships and contracts, ISS


2. Institutionary appointments


BIOETHICS UNIT

- Since 2007: Director of the Bioethics Unit of the ISS

COMMISSIONS, COMMITTEES AND OTHER INSTITUTIONARY APPPOINTMENTS


1) Appointment from the Council of Europe:
- Since 2016: Member of the “Ad hoc working group on the prohibition of making a financial gain from the human body"

2) Appointment from the Minister for Health:
- In 2018, on being appointed a member by the Minister for Health, he declined the post of President and was elected Vice President of the of the “National centre for the coordination of regional ethics committees for clinical trials of medicines and medical devices for human use” (Decree of the Minister for Health, 19 April 2018). On March 7, 2019, he was asked to study the feasibility of setting up the National centre at the ISS
- Since 2011: Member of the Working Group of the Italian National Health Council “Platelet gel from placental blood”
- Since 2007: Member of the Committee on hematopoietic cord blood stem cells (Decree of the Minister for Health, 20 February 2007)
3) Appointment from the President of the ISS:
- 2019: Member of the Working Group "Regulation for the management of conflict of interests" (Decree of the President of the Italian National Institute of Health n. 55/19 of 7 November 2019)
- 2019: Member of the Working Group of the National Institute of Health foreseen in the legislative decree 14 May 2019 n. 52 ("Implementation of the delegation for the reorganization and reform of the legislation on clinical trials of medicinal products for human use, pursuant to article 1, paragraphs 1 and 2, of the law 11 January 2018, n. 3) and in charge of identify “homogeneous criteria for the use of biological samples [for research purposes] taking into account the methods of access and acquisition of the patient's consent on the subsequent use of the sample taken” (art. 1, point 2, paragraph b)
- 2018: Delegate of the ISS on the Ministry for Health for the drafting of the Ministerial decrees putting the law 11 January 2018 n. 3 (Ethics Committees and clinical trials) into effect
- Since 2016: Responsible for the “Ethics” area of the “Website of knowledge” of the ISS
- Since 2014: Representative on the Medicines Utilization Monitoring Centre (Italian Medicines Agency)
- Since 2013: Delegate of the President of the ISS on the National Bioethics Committee
- Since 2011: Member of the Panel of Experts of the Italian National Health Council
- Since 2009: Member of the Commission for the Definition of Kidney Allocation Criteria
 (Italian National Transplant Centre)
- Since 2007: Member of the Ethics Committee of the General Hospital Fatebenefratelli
- Since 2006: Member of the National Commission for the Program of Crossover Kidney Transplant
- Since 2006: Member of the Interdepartmental Commission on Oncology of ISS
- Since 2005: Member of the Ethics Committee of the Neurological Institute Casimiro Mondino
- Since 2005: Member of the Working Group on the living donor crossover kidney transplant (Italian National Transplant Centre)
- Since 2004: Member of the Ethics Committee of ISS (2014-2017: Vice-Chair: since 2017: Chair)
- Since 2004: Member of the Ethics Committee of the Mediterranean Institute of Haematology
- Since 2004: Advisor of the United Nations Educational, Scientific and Cultural Organization (UNESCO) for the disciplinary area: Bioethics
4) Appointment from the President of the Joint Commission National Bioethics Committee – National Committee for Biosecurity, Biotechnology and Life Sciences (Presidency of the Council of Ministers):
- Expert for the Joint Commission (2009-2010) (Decree of the President of the Council of Ministers 17 February 2009)
- Member of the Commission on standardized informed consent for the storage of biological samples in biobanks (2008-2009)
5) Appointment from the Italian National Health Council:
- Member of the Working Group “Medical Humanities in the era of technological and IT medicine” (2018) 

6) Appointment from the President of the National Agency for New Technologies, Energy and the Sustainable Economic Development (ENEA):
- Since 2003: Member of the Bioethics Committee of ENEA
7) Appointment from the Director of the Italian National Transplant Centre:
- Since 2009: Member of the Advisory Committee for the authorisation of autologous-dedicated conservation of cord blood (Decree of the Minister of the Health 18 November 2009; Decree of the Minister of the Health 23 November 2012)
- Since 2007: Member of the Permanent Technical Council for Transplant
8) Appointment from the President of the Stazione Zoologica Anton Dohrn, Naples:
- Since 2011: Member of the Ethics Committee of the Stazione Zoologica Anton Dohrn
9) Appointment from the Director of the Italian National Blood Center:
- Since 2013: Member of the Working group on hyperimmune blood plasma
10) Appointment from the Pontifical Academy for Life:
- Since 2010: Member of the Working Group “Cord blood biobanks: ethical, juridical, social and cultural implications"
11) Other institutionary appointments
- Member of the Ethics Commission of the Italian Diplomatic Academy
- Member of the Ethics Think Tank “Synthetic Biology”, National Centre of Competence in Research (NCCR) Molecular Systems Engineering, University of Basel 
- Member of the Technical-Scientific Committee of the guidelines for autistic spectrum disorders (ISS)
-Advisor to the panel of experts of the guidelines on major traumas for ethical issues and the management of conflicts of interest (ISS)
- Member of the Ethics Group of the Working Table for monitoring the implementation of the National Dementia Plan
- Chair of the Expert Panel on end-of-life care. Azienda Ospedaliera San Giovanni Addolorata, Rome
- Member of the Scientific Committee of the master “Human ecology and life sciences: third millennium sustainability challenges” (Scuola di Alta Formazione e Studi Specializzati per Professionisti, Università Campus Biomedico di Roma, Università di Bari, Fédération Internationale des Associations de Médecins Catholiques - World Federation of the Catholic Medical Associations)
- Member of the ISS Temporary Mission Structures: 
  + Dementia: Prevention and care pathways, research, diagnosis and therapy
  + Health Inequalities
  + Undiagnosed sare diseases without a diagnosis

- Guest lecturer at the "International Seminars on Planetary Emergencies" of the Ettore Majorana Foundation and Centre for Scientific Culture
- Member of the National Ethics Committee for Health Protection in Correctional Facilities and Related Settings
- Member of the Steering Committee of the High Level Course on Medical Liability. Libera Università Maria SS. Assunta (LUMSA)
- Member of the Ethics Commission of the Consorzio Universitario per gli Studi Superiori e le Ricerche Applicate Studiorum
- Member of the ISS Task force on health inequalities
- Member of the Working Group for the European Code of Conduct of BBMRI.IT
- Columnist for “L’Osservatore Romano”
- Member of the Editorial Board of:
Clinical Research and Regulatory Affairs (since 2013)
International Journal of Clinical Therapeutics and Diagnosis (IJCTD) (since 2013)
- Since 2016: Member of the Technical and Scientific Committee of the Amyotrophic Lateral Sclerosis (ALS) Register of the Region Lazio.
- Since 2016: Member of the Ethics Committee Lazio-2
- 2015-2016: Advisor on the Ethics Committee Lazio-2
- Since 2015: Expert of the Animal Welfare Monitoring Committee of the ISS
- Since 2015: Member of the Ethics Committee for Scientific Research of the Libera Università Maria Ss. Assunta (LUMSA)
- Since 2015: Representative on the Office for Human Research Protections (OHRP)
- Since 2015: Member of the Ethics Board of the project “Darwin. Adapt to Survive. Expecting the unexpected and know how to respond”
- Since 2013: Ethics adviser of the Front Door of the Italian Advanced Translational Research Infrastructure (IATRIS)
- Since 2012: Member of the Working Group “Disposal of Hematopoietic Stem Cells” of the Italian Society of Hemapheresis and Cell Manipulation (SIdEM)
- Since 2012: Member of the Ethics Committee of Health Agency Rome C
- Since 2011: Member del Working Group on Ethical Issues of Alzheimer Europe
- Since 2011: Member of Working Group “Proposal of a regulation for research biobanks and of criteria for sample donation” of the Italian Node of “BBMRI: Biobanking and Biomolecular Resources Research Infrastructure”
- Since 2012: Ethics expert for the project “Developmental origins of healthy and unhealthy ageing: the role of maternal obesity” (Consiglio Nazionale delle Ricerche, European Commission)
- Since 2011: Ethics Advisor of the project “The impact of DEmographic Changes on Infectious DisEases transmission and control in middle/low income countries, DECIDE” (European Research Council and Bocconi University, Dondena Centre)
- Since 2010: Member of the Advisory Board of the project “Italy and its regions”, Institute of the Italian Encyclopaedia Treccani
- Since 2010: Member of the technical commission of the prize Alesini - Cittadinanzattiva - Amgen “Good practices in the patient-centred care”
- Since 2009: Member of the Advisory Board of “Clinical Trial Magnifier”
- 2009- 2010: Member of the International Advisory Board of the manual “Reviewing clinical trials: A guide for ethics committee” (Clinical Trials Centre, University of Hong Kong; Association for the Accreditation of Human Research Projects Protection Programs, Washington DC)
- Since 2000: Scientific director of courses of the ISS on the ethics of: clinical trials, public health, environmental and health risks 
12) Auditions at the Chamber of Deputies and the Senate of the Italian Republic, as a representative of the Istituto Superiore di Sanità:
- Hearing in the debate on the draft laws "Rules on informed consent and declarations of intention anticipated in health treatments". Chamber of Deputies, Social Affairs Committee, 31 March 2016
- Hearing in the debate on the draft laws "Rules on informed consent and advance treatment provisions". Senate, Hygiene and Health Commission, 1 June 2017

- Hearing in the examination of the draft legislative decree containing amendments to the legislative decree 6 November 2007, n. 200, for the implementation of directive 2005/28/EC, adopted in implementation of the delegation for the reorganization and reform of the legislation on clinical trials for medicinal products for human use. Chamber of Deputies, Social Affairs Commission, 26 March 2019
- Hearing in the examination of the proposals of law n. 2, by popular initiative, C. 1586 Cecconi and C. 1655 Rostan, bearing "Rejection of medical treatment and lawfulness of euthanasia". Chamber of Deputies, Social Affairs and Justice Commissions, 4 June 2019


3. Other appointments


- Since 2010: Professor at the International Master in BioLaw. Research Institute Biogem.
- Since 2002: Professor at the Master in Environmental Sciences of the Pontifical Regina  Apostolorum University and, since 2006, of the European University of Rome
- Since 2002: Member of the Ethical Core of the project “Genome-wide analyses of European twin and population cohorts to identify genes predisposing to common diseases”
- Since 2001: Professor of Environmental Ethics and of Public Health Ethics, Faculty of Bioethics - Pontifical University Regina Apostolorum
- 2001-2002: Professor of bioethics, Faculty of Medicine - Catholic University of the Sacred Heart
- Since 1999 to 2013: Entrusted of the section “Ethics of the Biology” of the journal “Biologi Italiani”
- Chairman to thesis of degree and doctorate in bioethics
- Advisor on bioethical issues to:
   + Canadian Institutes of Health Research (Government of Canada) / Instituts de Recherche en Santé du Canada (Gouvernement du Canada)
   + European Commission
   + Italian Data Protection Authority
   + Italian National Blood Centre
   + Italian National Transplant Centre
   + Italian Superior Council of Magistracy
   + European Science Foundation
   + Ministry of Health
   + Pontifical Council for Justice and Peace
   + Senate of the Italian Republic
   + UNESCO 

 

4. Research Projects

 

1) Scientific responsibility:
- President of the Ethics Committee of the Project “Mesenchymal stem cell-derived extracellular vesicles for the treatment of inflammatory bowel disease” (University of Padua; European Advanced Translational Research Infrastructure in Medicine – EATRIS; ESPERITE)
- Participating Unit "Bioethics", Project "Nosographic revision of vegetative states: application of behavioural analysis methods in the study of subjects in coma and vegetative state" (Ministry of Health; 2010-2012)
- Working Group "Bioethics", Program 1 of "Alleanza Contro il Cancro" (Alliance Against Cancer) on: "Reduction of disparities in the patients’ access to diagnostic and therapeutic resources", work package 5: "Establishment of a national information service on cancer" (2008-2010)
- EuroPHEN - European Public Health Ethics Network (Convention ISS/European Commission; Scientific responsible 2003-2006)

2) Partnership:
- I-Consent: Improving the guidelines for Informed Consent, including vulnerable populations, under a gender perspective (adivisor since 2017)
- RD-CONNECT: An integrated platform connecting registries, biobanks and clinical bioinformatics for rare disease research (since 2012)
- BBMRI: Biobanking and Biomolecular Resources Research Infrastructure (since 2010)
- EuEvidence: European Virtualized Infrastructure of Distributed ENvironments for Clustering E-science for medicine” (since 2010)
- The Network of Italian Oncologic Banks (RIBBO). Cooperating Unit 1: Bioethics (since 2009)
- ELIOS - Multicentric, randomized, double blind trial on the effects of the combined use of lithium salts and riluzol in the amyotrophic lateral sclerosis (ALS) (since 2009)
- EATRIS - The European Advanced Translational Research Infrastructure in Medicine (since 2007)
- AD Care - Alzheimer's Disease (AD) and antipsychotics: a long term, multicentre, double blind, randomised clinical trial (member of the Date and Safety Monitoring Board; since 2007)
- EUROCAN+PLUS - Feasibility Study for Coordination of National Cancer Activities (2006-2007)
- Bioethical issues in clinical experimentation or techniques utilizing ionizing radiations (since 2001)
- Retrieval and diffusion of information in the field of the bioethics by means of an integrated electronic system (since 1999)

3) Collaboration:
- Ethicsweb: Inter-connected European information and documentation system for ethics and science: European Ethics Documentation Centre (since 2008)
- Biometric Identification Technology Ethics (2004-2006)


5. Memberships


- Since 2018: Italian Society for History of Medicine
- Since 2010: Italian Society for Safety and Quality in Transplant (SISQT)
- Since 2009: Italian Society for Organ Transplantation (SITO)
- Since 2009: The Italian Society of Environment and Health (ISEH)
- Since 2008: European Public Health Law Network (EPHLN)
- Since 2004: National Institute for the Study, the Evaluation and the Prevention of the Risk in the Technological Activities (INRPAT)
- Since 2000: Italian Society for Bioethics and the Ethics Committees (SIBCE)
- Since 2000: Association of Scientists and Technologists for the Ethics of the Development (STES)
- Since 1995: European Countries Biologists Association
- Since 1990: Directive of the “International Communication Society"
- Since 1990: Scientific committee of the journal “Innovazione, Comunicazione, Sviluppo”